activation code for easy translator 12.5

SP1 KLF6 POLR2A KLF17 ZNF600 KLF9 YY1 HIC1 ZNF207 BRCA1 GCA IFIH1 NONHSAG029692.2 AHCTF1P1 FAP lnc-FAP-3 SP1 POLR2A ZNF600 DNMT3B BCL11A YY1 ZNF207 ZNF592 CTCF MAZ Acts as a tumor suppressor in melanocytic cells through regulation of cell proliferation and survival in a serine protease activity-independent manner.ĮPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER Promotes glioma cell invasion through the brain parenchyma by degrading the proteoglycan brevican. Enhances tumor growth progression by increasing angiogenesis, collagen fiber degradation and apoptosis and by reducing antitumor response of the immune system. Participates in the cell invasiveness towards the ECM in malignant melanoma cancers. Plays a role in tissue remodeling during development and wound healing. The plasma membrane form, in association with either DPP4, PLAUR or integrins, is involved in the pericellular proteolysis of the extracellular matrix (ECM), and hence promotes cell adhesion, migration and invasion through the ECM. Natural neuropeptide hormones for dipeptidyl peptidase are the neuropeptide Y (NPY), peptide YY (PYY), substance P (TAC1) and brain natriuretic peptide 32 (NPPB) (PubMed: 21314817). Also has dipeptidyl peptidase activity, exhibiting the ability to hydrolyze the prolyl bond two residues from the N-terminus of synthetic dipeptide substrates provided that the penultimate residue is proline, with a preference for Ala-Pro, Ile-Pro, Gly-Pro, Arg-Pro and Pro-Pro (PubMed: 10347120, 10593948, 16175601, 16223769, 16651416, 16410248, 17381073, 21314817, 24371721, 24717288). Both plasma membrane and soluble forms exhibit post-proline cleaving endopeptidase activity, with a marked preference for Ala/Ser-Gly-Pro-Ser/Asn/Ala consensus sequences, on substrate such as alpha-2-antiplasmin SERPINF2 and SPRY2 (PubMed: 14751930, 16223769, 16480718, 16410248, 17381073, 18095711, 21288888, 24371721). UniProtKB/Swiss-Prot Summary for FAP GeneĬell surface glycoprotein serine protease that participates in extracellular matrix degradation and involved in many cellular processes including tissue remodeling, fibrosis, wound healing, inflammation and tumor growth.

Activation code for easy translator 12.5